QGel
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QGel Inc. (www.qgelbio.com) a Swiss biotech company, recently commercialized QGel™ MT 3D Matrix (QGel™), a reputed synthetic hydrogel with over ten years of high-level scientific backing, including publications in Nature Biotechnology, PNAS, Advanced Materials and Biomaterials.
Among many of its applications, QGel™ can be used as a matrix for 3D cell culture and is particularly interesting for studies in regenerative medicine, cancer research and drug screening. The synthetic biological and biochemical components used to bioengineer QGel™ extracellular matrix (ECM) are what make QGel™ unique compared to currently available products. Protease-sensitive sites and cell-adhesion ligands, such as RGD, are key components of QGel™ that mimic essential features of natural ECM.
Unlike other synthetic products, QGel™ degrades like natural ECM, i.e. by cell-secreted and activated proteases, such as MMP (matrix metalloproteinase). QGel™ components that define the biological and biochemical characteristics of its matrix are like building-blocks that allow for QGel to be bioengineered on a molecular level. This building-block modularity gives QGel™ advantages over natural ‘gold standard’ matrices, where ‘what you get’ depends on the origin of the organism from which it was derived.
The ability to synthesize and bioengineer QGel™ offers scientists an exclusive possibility to adapt these biomimetic 3D cell culture models to specific cell types and to investigate different aspects of cell-matrix interaction in 3D. Since June 2010, QGel™ matrix products are available in sterile, ready-to-use vials manufactured under strict GMP conditions. Brochures for QGel products can be found here DOWNLOAD BROCHURES
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info@qgelbio.com
www.qgelbio.com
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