Culture of HepG2 liver cells on three dimensional polystyrene scaffolds enhances cell structure and function during toxicological challenge

(eng)  

Cultured cells are dramatically affected by the micro-environment in which they are grown. In this study, we have investigated whether HepG2 liver cells grown in three dimensional (3-D) cultures cope more effectively with the known cytotoxic agent, m...

Periodical:  J Anat  2007/08/23

Authors:  Bokhari, M., Carnachan, R. J., Cameron, N. R., Przyborski, S. A.

Keywords:  Adult, Alginates/chemistry, Biocompatible Materials/*chemistry, Cell Count, Cell Culture Techniques/methods, Cells, Cultured, Collagen/analysis/chemistry, Dental Pulp/chemistry/*physiology, Extracellular Matrix/chemistry/*physiology, Fibroblasts/chemistry/cytology, Glucuronic Acid, Hexuronic Acids, Humans, Polyglycolic Acid/*chemistry