Adipose tissue model using three-dimensional cultivation of preadipocytes seeded onto fibrous polymer scaffolds

(English)  

A better understanding of the mechanism of adipose tissue differentiation is of paramount importance in the development of therapeutic strategies for the treatment and prevention of obesity and type 2 diabetes mellitus. Optimal results using tissue c...

Periodical:  Tissue Engineering

Authors:  Kang, X. H., Xie, Y. B., Kniss, D. A.

Keywords:  Animals, Cell Differentiation, Cell Transformation, Neoplastic, Collagen, Culture Techniques/methods, Dogs, Enzyme Activation, Enzyme Precursors/*metabolism, Extracellular Matrix/*metabolism, Gelatinases/*metabolism, Gels, Hepatocyte Growth Factor/pharmacology, Kidney Tubules/cytology/*enzymology, Matrix Metalloproteinases, Membrane-Associated, Metalloendopeptidases/genetics/*metabolism, Protein Processing, Post-Translational, Transfection