Heterogeneity of human glioblastoma: Glutathione-S-transferase and methylguanine-methyltransferase

(English)  

The DNA repair and detoxifying enzymes, O-6-methylguanine-DNA-methyltransferase (MGMT) and glutathione-S-transferase (GST), may be responsible of poor response to alkylating agents in glioblastoma treatment. The methylation of MGMT promoter and the e...

Periodical:  Cancer Investigation

Authors:  Juillerat-Jeanneret, L., Bernasconi, C. C., Bricod, C., Gros, S., Trepey, S., Benhattar, J., Janzer, R. C.

Keywords:  BLOOD-GLUCOSE, collagen, CROSS-LINKING, CYTOTOXICITY, DEGRADATION, FIBERS, FIBROBLASTS, GLUTARALDEHYDE, implantable glucose sensor, MATRICES, MICRODIALYSIS, NDGA crosslinking, porous scaffold, SUBCUTANEOUS TISSUE