Three-dimensional neuroblastoma cell culture: proteomic analysis between monolayer and multicellular tumor spheroids

(English)  

Introduction Solid tumors, such as neuroblastoma (NB), are associated with a heterogeneous cell environment. Multicellular tumor spheroid (MCTS) cultures have been shown to better mimic growth characteristics of in vivo solid tumors. Because tumor sp...

Periodical:  Pediatric Surgery International

Authors:  Kumar, H. R., Zhong, X. L., Hoelz, D. J., Rescorla, F. J., Hickey, R. J., Malkas, L. H., Sandoval, J. A.

Keywords:  DIFFERENTIATION, FABRICATION, GROWTH, INTEGRATION, POLYMER SCAFFOLDS, PROTEIN, REGENERATION, RETINA