Ovarian normal and tumor-associated fibroblasts retain in vivo stromal characteristics in a 3-D matrix-dependent manner

(English)  

Objective. Due to a lack of experimental systems, little is known about ovarian stroma. Here, we introduce an in vivo-like 3-D system of mesenchymal stromal progression during ovarian tumorigenesis to support the study of stroma permissiveness in hum...

Periodical:  Gynecologic Oncology

Authors:  Quiros, R. M., Valianou, M., Kwon, Y., Brown, K. M., Godwin, A. K., Cukierman, E.

Keywords:  CFD analysis, DEVICES, FABRICATION, GRADIENTS, GROWTH, HEPATOCYTES, LIVER, MICROFABRICATION, MORPHOLOGY, optimized microstructure, POLYMER, RADIAL-FLOW BIOREACTOR, scaffold