Disease models of breast cancer

Periodical: Drug Discovery Today: Disease Models ISBN: 1740-6757  Number: 1  Pages: 9-16

Authors:Gupta, Piyush B., Kuperwasser, Charlotte

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Abstract
The development of novel breast cancer therapies depends on appropriate experimental models of disease pathogenesis. In recent years, there has been a proliferation of sophisticated models for breast cancer research. We describe here novel models that have particular relevance for drug development, and discuss the advantages and disadvantages of each model with respect to the various aspects of breast cancer pathogenesis.